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LGI3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501733640 Shop All Proteintech Group Inc Products
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50-173-3640 150 μL
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Catalog No. 50-173-3640 Supplier Proteintech Group Inc Supplier No. 219191AP150UL
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Description

Rabbit Polyclonal Antibody

The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodomit lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predomit auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.

Specifications

Antigen LGI3
Applications Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LGI3
Gene Accession No. Q8K406, Q8N145
Gene Alias LGI1 like protein 4, LGI3, LGIL4
Gene Symbols LGI3
Host Species Rabbit
Immunogen LGI3 Fusion Protein Ag16257
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 203190, 213469, 306013
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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