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Invitrogen™ LGP2 Monoclonal Antibody (6A6A3)
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Catalog No. PIMA531717
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100 μL
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PIMA531717 100 μL
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Catalog No. PIMA531717 Supplier Invitrogen™ Supplier No. MA531717
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Description

Mouse Monoclonal Antibody

MA5-31717 has been tested in indirect ELISA.

Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LGP2
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 6A6A3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene DHX58
Gene Accession No. Q96C10
Gene Alias B430001I08Rik; D11LGP2; D11lgp2e; DEXH (Asp-Glu-X-His) box polypeptide 58; DEXH-box helicase 58; DHX58; Lgp2; LPG2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; Probable ATP-dependent RNA helicase DHX58; protein D11Lgp2; Protein D11Lgp2 homolog; RGD1310093; RIG-I-like receptor 3; RIG-I-like receptor Lgp2; RLR; RLR-3; RNA helicase LGP2
Gene Symbols DHX58
Host Species Mouse
Immunogen Purified recombinant fragment of human DHX58 (AA: 479-678) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79132
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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