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LGP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 113551AP150UL

Encompass_Preferred

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Catalog No. 50-172-7087


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Description

Description

Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Specifications

Specifications

LGP2
Polyclonal
Unconjugated
DHX58
D11LGP2, D11lgp2e, DHX58, LGP2, Protein D11Lgp2 homolog, RIG I like receptor LGP2, RLR
Rabbit
Antigen Affinity Chromatography
RUO
303538, 79132, 80861
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q96C10, Q99J87
Dhx58
LGP2 Fusion Protein Ag1910
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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