LGR4 Monoclonal Antibody (6G8.B3.G5.C3), Rockland™

Mouse Monoclonal Antibody

Supplier:  Rockland Immunochemicals 200301B45S

Catalog No. 50-199-0577

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for human LGR4 protein. A BLAST analysis was used to suggest cross-reactivity with LGR4 from chimpanzee, orangutan and macaque based on 100% homology with the immunizing sequence. Cross-reactivity with LGR4 from other sources has not been determined.

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.

Specifications

• Antigen: LGR4
• Classification: Monoclonal
• Concentration: 1.13 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
• Gene Accession No.: Q9BXB1
• Gene Symbols: LGR4
• Immunogen: This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.
• Regulatory Status: RUO
• Gene ID (Entrez): 451088, 55366, 701736
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 6G8.B3.G5.C3
• Conjugate: Unconjugated
• Gene: LGR4
• Gene Alias: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; G protein-coupled receptor 48; G protein-coupled receptor GPR48; GPR48; G-protein coupled receptor 48; leucine rich repeat containing G protein-coupled receptor 4; leucine-rich repeat containing G protein-coupled receptor 4; leucine-rich repeat-containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4; LGR4
• Host Species: Mouse
• Quantity: 25 μL
• Primary or Secondary: Primary
• Target Species: Chimpanzee, Human, Rhesus Monkey
• Product Type: Antibody
• Isotype: IgG2b κ