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Invitrogen™ LILRA3 Polyclonal Antibody
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Catalog No. PIPA547349
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100 μg
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PIPA547349 100 μg
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Catalog No. PIPA547349 Supplier Invitrogen™ Supplier No. PA547349
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 30% cross-reactivity with recombinant human (rh) ILT2, rhILT4, ILT5 is observed, and less than 5% cross-reactivity with rhLIR5 and rhLIR7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).
TRUSTED_SUSTAINABILITY

Specifications

Antigen LILRA3
Applications Flow Cytometry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LILRA3
Gene Accession No. Q8N6C8
Gene Alias CD85 antigen-like family member E; CD85e; HM31; HM43; ILT6; ILT-6; Immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; leukocyte immunoglobulin like receptor A3; leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LILRA3; LIR4; LIR-4; Monocyte inhibitory receptor HM43/HM31
Gene Symbols LILRA3
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human LILRA3/CD85e Arg18-Glu439.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11026
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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