Invitrogen™ LILRA3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528902

Catalog No. PIPA528902

Description

Recommended positive controls: LILRA3-transfected 293T. Predicted reactivity: Rhesus Monkey (91%), Chimpanzee (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane region and is presumed to be a soluble receptor (Borges et al., 1997 [PubMed 9548455]).

Specifications

• Antigen: LILRA3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LILRA3
• Gene Alias: CD85 antigen-like family member E; CD85e; HM31; HM43; ILT6; ILT-6; Immunoglobulin-like transcript 6; leucocyte Ig-like receptor A3; leukocyte immunoglobulin like receptor A3; leukocyte immunoglobulin-like receptor 4; leukocyte immunoglobulin-like receptor A3; leukocyte immunoglobulin-like receptor subfamily A member 3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; LILRA3; LIR4; LIR-4; Monocyte inhibitory receptor HM43/HM31
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11026
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8N6C8
• Gene Symbols: LILRA3
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LILRA3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG