Invitrogen™ LILRA5 Monoclonal Antibody (711828)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524330

Catalog No. PIMA524330

Description

In direct ELISAs, no cross-reactivity with recombinant mouse ILT11/LILRA5, recombinant rat (rr) ILT11/LILRA5, rrLILRC2, recombinant human (rh) ILT4/CD85d, rhILT5/CD85a, or rhILT3/CD85k is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Leukocyte immunoglobulin-like receptor A5 (LILRA5) is a gene located on chromosome 19q13.42, encoding a protein that is part of the leukocyte immunoglobulin-like receptor (LILR) family. These receptors are primarily expressed on immune cells, such as natural killer cells, monocytes, and dendritic cells, and play a pivotal role in modulating immune responses. LILRA5 is thought to function as an activating receptor, influencing the activation and regulation of immune cell functions. It is implicated in processes such as antigen presentation, cytokine production, and phagocytosis, contributing to both innate and adaptive immune responses. Dysregulation of LILRA5 expression or function can impact immune homeostasis and has been associated with various autoimmune and inflammatory diseases. Research into LILRA5 aims to uncover its specific ligands and signaling pathways, with potential implications for therapeutic targeting in immune-related disorders.

Specifications

• Antigen: LILRA5
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: A6NI73
• Gene Symbols: LILRA5
• Immunogen: CHO-derived recombinant human LILRA5/CD85f Gly42-Arg268.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunocytochemistry
• Clone: 711828
• Conjugate: Unconjugated
• Gene: LILRA5
• Gene Alias: CD85; CD85 antigen-like family member F; CD85f; CD85f antigen; E030017K20; EG232801; Gm4878; ILT11; ILT-11; Immunoglobulin-like transcript 11; immunoglobulin-like transcript 11 protein; leucocyte Ig-like receptor A5; leukocyte Ig-like receptor 9; leukocyte immunoglobulin like receptor A5; leukocyte immunoglobulin-like receptor; leukocyte immunoglobulin-like receptor 9; Leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7; LILRA5; LILRB7; Lilrc1; LIR9; LIR-9
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 353514
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized