Invitrogen™ LILRA5 Polyclonal Antibody

Catalog No.	Quantity
PIPA547616	100 μg

Catalog No. PIPA547616 Supplier Invitrogen™ Supplier No. PA547616

Description

Sheep Polyclonal Antibody

In direct ELISAs, approximately 30% cross-reactivity with recombinant rat (rr) LILRC1 is observed and approximately 15% cross-reactivity with rrLILRC2 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Leukocyte immunoglobulin-like receptor A5 (LILRA5) is a gene located on chromosome 19q13.42, encoding a protein that is part of the leukocyte immunoglobulin-like receptor (LILR) family. These receptors are primarily expressed on immune cells, such as natural killer cells, monocytes, and dendritic cells, and play a pivotal role in modulating immune responses. LILRA5 is thought to function as an activating receptor, influencing the activation and regulation of immune cell functions. It is implicated in processes such as antigen presentation, cytokine production, and phagocytosis, contributing to both innate and adaptive immune responses. Dysregulation of LILRA5 expression or function can impact immune homeostasis and has been associated with various autoimmune and inflammatory diseases. Research into LILRA5 aims to uncover its specific ligands and signaling pathways, with potential implications for therapeutic targeting in immune-related disorders.

Specifications

• Antigen: LILRA5
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: LILRA5
• Gene Accession No.: 0
• Gene Alias: CD85; CD85 antigen-like family member F; CD85f; CD85f antigen; E030017K20; EG232801; Gm4878; ILT11; ILT-11; Immunoglobulin-like transcript 11; immunoglobulin-like transcript 11 protein; leucocyte Ig-like receptor A5; leukocyte Ig-like receptor 9; leukocyte immunoglobulin like receptor A5; leukocyte immunoglobulin-like receptor; leukocyte immunoglobulin-like receptor 9; Leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7; LILRA5; LILRB7; Lilrc1; LIR9; LIR-9
• Gene Symbols: LILRA5
• Host Species: Sheep
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse LILRC1 Gln17-Asn248.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 232801
• Target Species: Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG