Invitrogen™ LILRA5 Recombinant Rabbit Monoclonal Antibody (018)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA530646

Catalog No. PIMA530646

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Human LILRA5.

Leukocyte immunoglobulin-like receptor A5 (LILRA5) is a gene located on chromosome 19q13.42, encoding a protein that is part of the leukocyte immunoglobulin-like receptor (LILR) family. These receptors are primarily expressed on immune cells, such as natural killer cells, monocytes, and dendritic cells, and play a pivotal role in modulating immune responses. LILRA5 is thought to function as an activating receptor, influencing the activation and regulation of immune cell functions. It is implicated in processes such as antigen presentation, cytokine production, and phagocytosis, contributing to both innate and adaptive immune responses. Dysregulation of LILRA5 expression or function can impact immune homeostasis and has been associated with various autoimmune and inflammatory diseases. Research into LILRA5 aims to uncover its specific ligands and signaling pathways, with potential implications for therapeutic targeting in immune-related disorders.

Specifications

• Antigen: LILRA5
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: A6NI73
• Gene Symbols: LILRA5
• Immunogen: Recombinant Human LILRA5 Protein (Met1-Arg268).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA
• Clone: 018
• Conjugate: Unconjugated
• Gene: LILRA5
• Gene Alias: CD85; CD85 antigen-like family member F; CD85f; CD85f antigen; E030017K20; EG232801; Gm4878; ILT11; ILT-11; Immunoglobulin-like transcript 11; immunoglobulin-like transcript 11 protein; leucocyte Ig-like receptor A5; leukocyte Ig-like receptor 9; leukocyte immunoglobulin like receptor A5; leukocyte immunoglobulin-like receptor; leukocyte immunoglobulin-like receptor 9; Leukocyte immunoglobulin-like receptor subfamily A member 5; leukocyte immunoglobulin-like receptor subfamily A member 5 soluble; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 7; LILRA5; LILRB7; Lilrc1; LIR9; LIR-9
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 353514
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid