Invitrogen™ LILRB2 Monoclonal Antibody (01)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531038

Catalog No. PIMA531038

Description

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human LILRB2/ILT4/LIR-2.

LILRB2 (ILT4) gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: LILRB2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q8N423
• Gene Symbols: LILRB2
• Immunogen: Recombinant Human LILRB2/ILT4/LIR-2 Protein (Met1-Val461).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 01
• Conjugate: Unconjugated
• Gene: LILRB2
• Gene Alias: CD85 antigen-like family member D; CD85D; CD85d antigen; Ig-like transcript 4; ILT4; ILT-4; leucocyte Ig-like receptor B2; leukocyte immunoglobulin like receptor B2; leukocyte immunoglobulin-like receptor subfamily B member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; LILRB2; Lilrb3; LIR2; LIR-2; LIR2CD85D; MIR10; MIR-10; MIR10LILRA6; monocyte/macrophage immunoglobulin-like receptor 10; myeloid inhibitory receptor 10; Neutrophil immunoglobulin-like receptor 1; Nilr1; NILR-1; paired-Ig-like receptor B; Pirb; type 1 one-pass transmembrane Ig-like receptor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10288
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid