Invitrogen™ LILRB5 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547442

Catalog No. PIPA547442

Description

In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) LIR-4/ILT6 is observed, and approximately 10% cross-reactivity with rhILT5, rhLIR-5/ILT3, rhLIR-6, and rhLILRA5 is observed, and less than 5% cross-reactivity with rhILT2, rhILT4, and rhLIR-7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.

Specifications

• Antigen: LILRB5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LILRB5
• Gene Alias: CD85 antigen-like family member C; CD85C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin like receptor B5; leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LILRB5; LIR8; LIR-8
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10990
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: O75023
• Gene Symbols: LILRB5
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human LILRB5/CD85c/LIR-8 Arg18-His456.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG