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Invitrogen™ LILRB5 Polyclonal Antibody
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Catalog No. PIPA547442
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100 μg
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PIPA547442 100 μg
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Catalog No. PIPA547442 Supplier Invitrogen™ Supplier No. PA547442
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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) LIR-4/ILT6 is observed, and approximately 10% cross-reactivity with rhILT5, rhLIR-5/ILT3, rhLIR-6, and rhLILRA5 is observed, and less than 5% cross-reactivity with rhILT2, rhILT4, and rhLIR-7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

This gene is a member of the leukocyte immunoglobulin-likereceptor (LIR) family, which is found in a gene cluster atchromosomal region 19q13.4. The encoded protein belongs to thesubfamily B class of LIR receptors which contain two or fourextracellular immunoglobulin domains, a transmembrane domain, andtwo to four cytoplasmic immunoreceptor tyrosine-based inhibitorymotifs (ITIMs). Several other LIR subfamily B receptors areexpressed on immune cells where they bind to MHC class I moleculeson antigen-presenting cells and inhibit stimulation of an immuneresponse. Multiple transcript variants encoding different isoformshave been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LILRB5
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene LILRB5
Gene Accession No. O75023
Gene Alias CD85 antigen-like family member C; CD85C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin like receptor B5; leukocyte immunoglobulin-like receptor 8; Leukocyte immunoglobulin-like receptor subfamily B member 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; LILRB5; LIR8; LIR-8
Gene Symbols LILRB5
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant human LILRB5/CD85c/LIR-8 Arg18-His456.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10990
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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