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Invitrogen™ LIMK1 Monoclonal Antibody (175CT3.2.5)
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Catalog No. PIMA537486
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400 μL
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Catalog No. Quantity
PIMA537486 400 μL
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Catalog No. PIMA537486 Supplier Invitrogen™ Supplier No. MA537486
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Description

Mouse Monoclonal Antibody

LIMK1 Monoclonal Antibody for Western Blot

LIMK1 is a serine/threonine kinase involved in regulation of actin cytoskeletal changes via phosphorylation of cofilin. LIMK1 has also been implicated in brain development. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LIMK1
Applications Western Blot
Classification Monoclonal
Clone 175CT3.2.5
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene LIMK1
Gene Accession No. P53667, P53668
Gene Alias EC 2.7.11.1; kinase LIMK1; KIZ-1; LIM domain kinase 1; lim kinase 1; LIM motif-containing protein kinase; LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing, protein kinase 1; Limk; LIMK1; LIMK-1
Gene Symbols LIMK1
Host Species Mouse
Immunogen KLH conjugated synthetic peptide between 479-508 amino acids from the C-terminal region of human LIMK1.
Purification Method Ammonium sulfate precipitation
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16885, 3984
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgM κ
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