LIMK1 Mouse anti-Human, Clone: OTI 7C3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF503007

Catalog No. 50-166-1804

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.

Specifications

• Antigen: LIMK1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: LIMK1
• Gene Alias: LIMK, LIMK-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3984
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI 7C3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P53667
• Gene Symbols: LIMK1
• Immunogen: Full length human recombit protein of human LIMK1 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b