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LIMK1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984958
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100 μL
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50-198-4958 100 μL
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Catalog No. 50-198-4958 Supplier Bioss Supplier No. BS2775R
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Rabbit Polyclonal Antibody

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.

Specifications

Antigen LIMK1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene LIMK1
Gene Accession No. P53667
Gene Alias EC 2.7.11.1; kinase LIMK1; KIZ-1; LIM domain kinase 1; LIM motif-containing protein kinase; LIM motif-containing protein kinase 1; LIM-domain containing protein kinase 1; LIM-domain containing, protein kinase; LIM-domain containing, protein kinase 1; LIMK; Limk1; LIMK-1
Gene Symbols LIMK1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human LIMK1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3984
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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