Invitrogen™ LIMS1 Monoclonal Antibody (5G7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515876

Catalog No. PIMA515876

Description

MA5-15876 targets PINCH in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15876 immunogen is purified recombinant fragment of human PINCH expressed in E. Coli. . MA5-15876 detects PINCH which has a predicted molecular weight of approximately 37kDa.

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: LIMS1
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: P48059
• Gene Symbols: LIMS1
• Immunogen: Purified recombinant fragment of human PINCH expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 3987
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Clone: 5G7
• Conjugate: Unconjugated
• Gene: LIMS1
• Gene Alias: 2310016J22Rik; 4921524A02Rik; AI507642; AU021743; AW551584; C430041B13Rik; LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIM zinc finger domain containing 1; LIMS1; Lims1l; LIM-type zinc finger domains 1; Particularly interesting new Cys-His protein 1; PINCH; PINCH1; PINCH-1; renal carcinoma antigen NY-REN-48; RGD1560732; senescent cell antigen
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1