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Invitrogen™ LIMS1 Polyclonal Antibody
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Catalog No. PIPA530240
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100 μL
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PIPA530240 100 μL
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Catalog No. PIPA530240 Supplier Invitrogen™ Supplier No. PA530240
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A549, HeLa, HCT116. Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Zebrafish (95%), Xenopus laevis (97%), Pig (98%), Chicken (95%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LIMS1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.88 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene LIMS1
Gene Accession No. P48059
Gene Alias 2310016J22Rik; 4921524A02Rik; AI507642; AU021743; AW551584; C430041B13Rik; LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; LIM zinc finger domain containing 1; LIMS1; Lims1l; LIM-type zinc finger domains 1; Particularly interesting new Cys-His protein 1; PINCH; PINCH1; PINCH-1; renal carcinoma antigen NY-REN-48; RGD1560732; senescent cell antigen
Gene Symbols LIMS1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human LIMS1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3987
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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