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LIN7B Mouse anti-Human, Clone: OTI1G2, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF501513

Encompass_Preferred

Catalog No. 50-166-0523


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ACCN3 acid-evoked currents by stabilizing the channel at the cell surface.
Specifications

Specifications

LIN7B
Monoclonal
Unconjugated
LIN7B
LIN-7B, MALS-2, MALS2, VELI2
Mouse
Affinity Chromatography
RUO
64130
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Western Blot
OTI1G2
PBS with 8% trehalose and no preservative; pH 7.3
Q9HAP6
LIN7B
Full length human recombit protein of human LIN7B produced in HEK293T cell.
100 μg
Primary
Human
Antibody
IgG1
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