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Invitrogen™ LIN7C Polyclonal Antibody
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Catalog No. PIPA562320
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100 μL
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PIPA562320 100 μL
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Catalog No. PIPA562320 Supplier Invitrogen™ Supplier No. PA562320
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: NAVREVYEHV YETVDISSSP EVRAN Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LIN7C
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LIN7C
Gene Accession No. Q9NUP9
Gene Alias 9130007B12Rik; AI303698; AU019331; AW125731; D2Ertd520e; EGK_06400; fb75b09; FLJ11215; lin 7 homolog c; lin-7 homolog C; lin-7 homolog C (C. elegans); lin-7 homolog C, crumbs cell polarity complex component; LIN-7 protein 3; Lin7c; LIN-7C; lin-7-C; lin7c protein; MALS3; MALS-3; Mammalian lin-seven protein 3; mLin7C; neuroepithelial polarity protein; protein lin-7 homolog C; Protein lin-7-like protein C; Unknown (protein for MGC:140723); Veli3; veli-3; veli-3 protein; vertebrate homolog of C. elegans Lin-7 type 3; vertebrate lin-7 homolog 3; wu:fb75b09; zgc:101881
Gene Symbols LIN7C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LIN7C. Recombinant protein control fragment (Product #RP-99522).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55327
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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