LIN7C Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9621	Proteintech Group Inc 146561AP150UL	150 μL

Description

Protein assembly at the post synaptic density (PSD) of neuronal synapses is mediated in part by protein interactions with PDZ (PSD-95/discs large/zona occludens-1) motifs. The Mammalian LIN-7 (MALS) proteins are a family of small synaptic proteins that are the mammalian homologs of LIN-7, a C. elegans protein essential for vulval development. MALS proteins are also known as Veli (Vertebrate Lin-7) proteins. MALS-3 mRNA is most abundant in kidney, followed by brain, liver, thymus and heart. MALS-3 is undetectable in spleen. In cultured cortical neurons, MALS proteins are clustered together with PSD-95 and NMDA-type glutamate receptors. MALS proteins are suggested to have roles in regulating the recruitment of neurotransmitter receptors to the PSD and in the assembly of proteins involved in synaptic vesicle exocytosis and synaptic junctions.

Specifications

• Antigen: LIN7C
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O88952, Q792I0, Q9NUP9
• Gene ID (Entrez): 22343, 55327, 60442
• Immunogen: LIN7C Fusion Protein Ag6265
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: LIN7C

• Concentration: 0.25 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: LIN 7 C, lin 7 homolog C (C. elegans), LIN 7C, LIN7C, MALS 3, MALS3, Mammalian lin seven protein 3, Protein lin 7 homolog C, Veli 3, VELI3, Vertebrate lin 7 homolog 3
• Gene Symbols: Lin7c
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody