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Invitrogen™ LINGO1 Polyclonal Antibody
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Catalog No. PIPA531282
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100 μL
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Catalog No. Quantity
PIPA531282 100 μL
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Catalog No. PIPA531282 Supplier Invitrogen™ Supplier No. PA531282
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: LINGO1-transfected 293T. Predicted reactivity: Mouse (99%), Rat (99%), Chicken (92%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LINGO1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene LINGO1
Gene Accession No. Q96FE5
Gene Alias 4930471K13Rik; AV148400; LERN1; leucine rich repeat and Ig domain containing 1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; Lingo1; LINGO-1; LRRN6A; UNQ201; UNQ201/PRO227
Gene Symbols LINGO1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human LINGO1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315691, 84894
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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