Invitrogen™ LINGO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533890

Catalog No. PIPA533890

Description

LINGO1 Polyclonal Antibody for IHC (P)

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt].

Specifications

• Antigen: LINGO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LINGO1
• Gene Alias: 4930471K13Rik; AV148400; LERN1; leucine rich repeat and Ig domain containing 1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; Lingo1; LINGO-1; LRRN6A; UNQ201; UNQ201/PRO227
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100061441, 100155465, 100344366, 235402, 315691, 487660, 520694, 84894
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.6 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q96FE5, Q9D1T0
• Gene Symbols: LINGO1
• Immunogen: Synthetic 17 amino acid peptide from internal region of human LINGO1.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Pig, Horse, Zebrafish
• Product Type: Antibody
• Isotype: IgG