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Invitrogen™ LINGO1 Polyclonal Antibody
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Catalog No. PIPA597210
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100 μL
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PIPA597210 100 μL
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Catalog No. PIPA597210 Supplier Invitrogen™ Supplier No. PA597210
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: CPPRCECSAQ DRAVLCHRKR FVAVPEGIPT ETRLLDLGKN RIKTLNQDEF ASFPHLEELE LNENIVSAVE PGAFNNLFNL RTLGLRSNRL KLIPLGVFTG LSNLTKLDIS ENKIVILLDY MFQDLYNLKS LEVGDNDLVY ISHRAFSGLN SLEQLTLEKC NLTSIPTEAL SHLHGLIVLR LRHLNINAIR DYSFKRLYR; Positive Samples: MCF-7, A-549, K-562, Mouse testis, Mouse lung; Cellular Location: Cell membrane, Single-pass type I membrane protein.

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen LINGO1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LINGO1
Gene Accession No. Q96FE5, Q9D1T0
Gene Alias 4930471K13Rik; AV148400; LERN1; leucine rich repeat and Ig domain containing 1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobulin domain-containing protein 1; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; Leucine-rich repeat neuronal protein 6A; Lingo1; LINGO-1; LRRN6A; UNQ201; UNQ201/PRO227
Gene Symbols LINGO1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 42-240 of human LINGO1 (NP_1161974).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 235402, 84894
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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