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Invitrogen™ LIPC Polyclonal Antibody
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Catalog No. PIPA5102411
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100 μL
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PIPA5102411 100 μL
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Catalog No. PIPA5102411 Supplier Invitrogen™ Supplier No. PA5102411
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total LIPC.

The Lipase family belongs to one of the most robust genetic superfamilies found in living organisms that includes esterases and thioesterases. Lipase gene products are related by tertiary structure rather than primary amino acid sequence. Balancing the composition and the transport of lipoproteins in human plasma is essential for normal body function and is mediated in part by Hepatic Lipase, also known as HL or LIPC. Rare deficiencies in Hepatic Lipase have been identified in humans which lead to pathologic levels of circulating lipoprotein particles; this condition is associated with coronary artery disease (CAD). Hepatic Lipase is regulated by thyroid hormones and has a dual function as a triglyceride hydrolase and a ligand/bridging factor for receptor-mediated lipoprotein uptake. Hepatic Lipase localizes to the endothelial surfaces of extrahepatic tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LIPC
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene LIPC
Gene Accession No. P07867, P11150, P27656
Gene Alias AI256194; HDLCQ12; hepatic lipase; hepatic triacylglycerol lipase; HL; Hpl; HTGL; lipase C; lipase C, hepatic type; lipase member C; lipase, hepatic; LIPC; LIPH; Triacylglycerol lipase
Gene Symbols LIPC
Host Species Rabbit
Immunogen A synthesized peptide derived from human LIPC(Accession P11150), corresponding to amino acid residues R281-E331.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15450, 24538, 3990
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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