Invitrogen™ LIPG Polyclonal Antibody, DyLight™ 650

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522912

Catalog No. PIPA522912

Description

This antibody does not react with mouse endothelial lipase. Predicted to react with monkey based on 100% sequence homology. Does not appear to recognize mouse.

LIPG (Lipase G, Endohelial type) is an endothelial lipase which is a novel member of the lipoprotein lipase gene family. LIPG is synthesized by endothelial cells and functions at the site of synthesis. LIPG most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed LIPG has been shown to reduce HDL cholesterol levels, whereas an LIPG deficiency appears to be effective in elevating HDL cholesterol levels in animals. LIPG has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. Also, LIPG is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. LIPG is a carboxyl esterase that hydrolyzes high density lipoproteins, emulsifies triglycerides, is essential for the efficient digestion of dietary fats and can bind to heparin.

Specifications

• Antigen: LIPG
• Classification: Polyclonal
• Conjugate: DyLight 650
• Gene: LIPG
• Gene Alias: 3110013K01Rik; EDL; EL; endothelial cell-derived lipase; Endothelial lipase; endothelial-derived lipase; lipase; lipase G; lipase G, endothelial type; lipase, endothelial; LIPG; lipoprotein lipase H; lipose, endothelial; mEDL; PL; PRO719; UNQ387/PRO719
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9388
• Content And Storage: 4°C, store in dark
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 50mM sodium borate with 0.05% sodium azide
• Gene Accession No.: Q9Y5X9
• Gene Symbols: LIPG
• Immunogen: A C-terminal synthetic peptide made to human Endothelial Lipase.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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