Lipoamide Dehydrogenase Polyclonal Antibody, HRP, Rockland™

Rabbit Polyclonal Antibody

Supplier:  Rockland Immunochemicals 2004360S

Catalog No. 50-199-1111

Description

Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Lipoamide Dehydrogenase is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified Lipoamide Dehydrogenase [Porcine Heart]. Cross reactivity against Lipoamide Dehydrogenase from other sources is unknown.

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

Specifications

• Antigen: Lipoamide Dehydrogenase
• Classification: Polyclonal
• Conjugate: HRP
• Gene: Dld
• Gene Alias: aei; after eight protein; BOS_4234; branched chain alpha-keto acid dehydrogenase complex subunit E3; deltaD; deltaD transmembrane protein; delta-like protein D; diaphorase; Dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex); dihydrolipoamide: NAD+ oxidoreductase; Dihydrolipoyl dehydrogenase, mitochondrial; DLD; DLDD; DLDH; E3; E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex; GCSL; Glycine cleavage system L protein; glycine cleavage system protein L; LAD; lipoamide dehydrogenase; lipoamide reductase; lipoyl dehydrogenase; OTTHUMP00000206744; OTTHUMP00000206746; OTTHUMP00000206748; OTTHUMP00000206749; PH; PHE 3; PHE3; sc:d0402
• Host Species: Rabbit
• Quantity: 25 μL
• Primary or Secondary: Primary
• Target Species: Pig
• Product Type: Antibody

• Applications: ELISA, Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
• Gene Accession No.: P09623
• Gene Symbols: Dld
• Immunogen: Lipoamide Dehydrogenase [Porcine Heart]
• Regulatory Status: RUO
• Gene ID (Entrez): 397129
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized