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  5. Tocris Bioscience™ Liproxstatin-1 hydrochloride

Tocris Bioscience™ Liproxstatin-1 hydrochloride
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Catalog No. 61135
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25 mg
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Catalog No. Quantity
61-135 5 mg
61-132-5 25 mg
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Catalog No. 61-135 Supplier Tocris Bioscience™ Supplier No. 6113/5
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Description

Additional Apoptosis-related Compounds

Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor (IC50 = 22 nM). Protects human renal proximal tubule cells from 1S,3R-RSL3 (Cat.No. 6118) -induced cell death in vitro. Inhibits acute renal failure and prolongs survival in Gpx4 knockdown mice. Also mitigates tissue damage in an in vivo hepatic ischemia/reperfusion model.

Specifications

Synonym N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2′(1′H)-quinoxalin]-3′-amine hydrochloride
Quantity 5 mg
Target Ferroptosis Inhibitors
Molecular Formula C19H21ClN4.HCl
Formula Weight 377.31
Purity 98%
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