Invitrogen™ LIS1 Polyclonal Antibody

Catalog No.	Quantity
PIPA518048	100 μg

Catalog No. PIPA518048 Supplier Invitrogen™ Supplier No. PA518048

Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine, mouse and porcine based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.

Specifications

• Antigen: LIS1
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: PAFAH1B1
• Gene Accession No.: P43034, P63004
• Gene Alias: HAMAP-Rule:MF_03141}; Lis1; Lis-1; LIS-1 {ECO:0000255; LIS2; lissencephaly 1 protein; lissencephaly-1 protein; lissencephaly-1 protein {ECO:0000255; MDCR; MDS; Mdsh; MGC25297; Miller-Dieker syndrome chromosome region; MMS10-U; Ms10u; NudF; PAF acetylhydrolase 45 kDa subunit; PAF acetylhydrolase 45 kDa subunit {ECO:0000255; PAFAH; PAF-AH 45 kDa subunit; PAF-AH 45 kDa subunit {ECO:0000255; PAFAH alpha; PAF-AH alpha; PAFAH alpha {ECO:0000255; PAF-AH alpha {ECO:0000255; PAF-AH beta; Pafah1b1; Pafaha; platelet activating factor acetylhydrolase 1b regulatory subunit 1; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform variant; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255; platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); RP23-194P5.2
• Gene Symbols: PAFAH1B1
• Host Species: Goat
• Immunogen: Synthetic peptide sequence (TGSVDQTVKVWECR) corresponding to the C-terminus amino acids of PAFAH1B1 (aa 397-410).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5048, 83572
• Target Species: Human, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG