Invitrogen™ LIS1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570188

Catalog No. PIPA570188

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

VAMP7 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family, localizing to late endosomes and lysosomes. VAMP7 is thought to mediate the fusion of endosomes to their target lysosomes as well as other exocytosis events during phagocytosis and neuritogenesis. VAMP7 interacts with the VPS9 ankyrin repeat protein VARP, a protein that localizes to early endosomes and thought to regulate endosome dynamics. Together with CD82, VAMP7 can modulate the signaling of EGFR by regulating its endocytosis from the plasma membrane.

Specifications

• Antigen: LIS1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PAFAH1B1
• Gene Alias: HAMAP-Rule:MF_03141}; Lis1; Lis-1; LIS-1 {ECO:0000255; LIS2; lissencephaly 1 protein; lissencephaly-1 protein; lissencephaly-1 protein {ECO:0000255; MDCR; MDS; Mdsh; MGC25297; Miller-Dieker syndrome chromosome region; MMS10-U; Ms10u; NudF; PAF acetylhydrolase 45 kDa subunit; PAF acetylhydrolase 45 kDa subunit {ECO:0000255; PAFAH; PAF-AH 45 kDa subunit; PAF-AH 45 kDa subunit {ECO:0000255; PAFAH alpha; PAF-AH alpha; PAFAH alpha {ECO:0000255; PAF-AH alpha {ECO:0000255; PAF-AH beta; Pafah1b1; Pafaha; platelet activating factor acetylhydrolase 1b regulatory subunit 1; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform; platelet activating factor acetylhydrolase 45 kDa subunit brain isoform variant; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); platelet-activating factor acetylhydrolase beta subunit (PAF-AH beta); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255; platelet-activating factor acetylhydrolase, isoform 1b, beta1 subunit; platelet-activating factor acetylhydrolase, isoform 1b, subunit 1; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); RP23-194P5.2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 18472, 5048
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P43034, P63005
• Gene Symbols: PAFAH1B1
• Immunogen: synthetic peptide directed towards the N terminal region of human LIS1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG