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  5. Tocris Bioscience™ LJI308

Tocris Bioscience™ LJI308
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Catalog No. 67545
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM)

LJI308 is a potent pan-ribosomal S6 protein kinase (RSK) inhibitor (IC50 values are 4 to 13 nM). Displays selectivity for RSK isoforms over other kinases. Inhibits RSK-dependent Y-box binding protein 1 (YB-1) phosphorylation in vitro. Suppresses growth of triple negative breast cancer cell lines.

Specifications

Chemical Name or Material 2,6-Difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]phenol
CAS 1627709-94-7
Quantity 5 mg
Molecular Formula C21H18F2N2O2
Formula Weight 368.38
Purity 98%
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