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Invitrogen™ LKB1 Monoclonal Antibody (4H12)
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Catalog No. PIMA515729
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100 μL
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Catalog No. Quantity
PIMA515729 100 μL
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Catalog No. PIMA515729 Supplier Invitrogen™ Supplier No. MA515729
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Description

Mouse Monoclonal Antibody

MA5-15729 targets STK11 in indirect ELISA, FACS and WB applications and shows reactivity with Human, mouse, and Non-human primate samples. The MA5-15729 immunogen is purified recombinant fragment of human STK11 expressed in E. Coli. . MA5-15729 detects STK11 which has a predicted molecular weight of approximately 54kDa.

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LKB1
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 4H12
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene STK11
Gene Accession No. Q15831, Q9WTK7
Gene Alias AA408040; CAMK group; CAMKL family; hLKB1; liver kinase B1; Liver kinase B1 homolog; LKB 1; LKB1; LKB-1; LKB1(S); Par-4; PJS; polarization-related protein LKB1; R75140; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11; STK11
Gene Symbols STK11
Host Species Mouse
Immunogen Purified recombinant fragment of human STK11 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20869, 6794
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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