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LKB1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 50559536 Shop All Proteintech Group Inc Products
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50-559-536 150 μL
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Catalog No. 50-559-536 Supplier Proteintech Group Inc Supplier No. 107461AP150UL
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Description

Rabbit Polyclonal Antibody

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.

Specifications

Antigen LKB1
Applications Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene STK11
Gene Accession No. D4AE59, Q15831, Q9WTK7
Gene Alias LKB1, PJS, serine/threonine kinase 11, STK11
Gene Symbols Stk11
Host Species Rabbit
Immunogen LKB1 Fusion Protein Ag1048
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20869, 314621, 6794
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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