Invitrogen™ LLGL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554634

Catalog No. PIPA554634

Description

Immunogen sequence: TKYGQGFYLI SPSEFERFSL STKWLVEPRC LVDSAETKNH RPGNGAGPKK APSRARNSGT QSDGEEKQPG LVMERALLSD ERVLKEIQST LEGDRGSGNW RSHRAAVGCS LSNGGAE Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 76%.

LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.

Specifications

• Antigen: LLGL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LLGL2
• Gene Alias: 9130006H11Rik; HGL; Hugl-2; human giant larvae homolog; lethal giant larvae homolog 2; lethal giant larvae homolog 2 (Drosophila); lethal giant larvae homolog 2, scribble cell polarity complex component; lethal giant larvae-like protein 2; Lethal(2) giant larvae protein homolog 2; LGL2; LLGL scribble cell polarity complex component 2; Llgl2; LLGL2, scribble cell polarity complex component; Llglh2; RGD1560307
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3993
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6P1M3
• Gene Symbols: LLGL2
• Immunogen: Recombinant protein corresponding to Human LLGL2. Recombinant protein control fragment (Product #RP-93174).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov