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  5. Tocris Bioscience™ LM22B 10

Tocris Bioscience™ LM22B 10
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Catalog No. 603710
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60-371-0 10 mg
60-375-0 50 mg
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Catalog No. 60-371-0 Supplier Tocris Bioscience™ Supplier No. 6037/10
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Description

TrkB and TrkC agonist; brain penetrant

LM22B 10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant.

Specifications

Chemical Name or Material 2,2′,2′,2′′′-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
CAS 342777-54-2
Quantity 10 mg
Molecular Formula C27H33ClN2O4
Purity 98%
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