Invitrogen™ LMBR1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA553452

Catalog No. PIPA553452

Description

Immunogen sequence: FTVMGQLLVK PTILEDLDEQ IYIITLEEEA LQRRLNGLSS SVEYNIMELE QELENVKTLK TKLERRKKAS AWERN Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.

Specifications

• Antigen: LMBR1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lmbr1
• Gene Alias: 1110048D14Rik; ACHP; AU017641; C7orf2; DIF14; Differentiation-related gene 14 protein; FLJ11665; limb development membrane protein 1; limb region 1; limb region 1 homolog; limb region 1 protein; Limb region 1 protein homolog; Lmbr1; LSS; PPD2; THYP; TPT; Unknown (protein for MGC:134350); ZRS
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64327
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8WVP7
• Gene Symbols: Lmbr1
• Immunogen: Recombinant protein corresponding to Human LMBR1. Recombinant protein control fragment (Product #RP-91225).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG