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LMO2 Recombinant Rabbit Monoclonal Antibody (13H1L2), Invitrogen™

Catalog No. PI701156
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100 μg
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Catalog No. Quantity
PI701156 100 μg
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Catalog No. PI701156 Supplier Thermo Scientific Supplier No. 701156

Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with non-human primate, mouse, rabbit and rat based on sequence homology. Intact IgG appears on a non-reducing gel as ∽150 kDa band and upon reduction generating a ∽25 kDa light chain band and a ∽50 kDa heavy chain. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LMO2
Applications Western Blot
Classification Recombinant Monoclonal
Clone 13H1L2
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene Lmo2
Gene Accession No. P25791
Gene Alias cysteine-rich protein TTG-2; LIM domain only 2; LIM domain only 2 (rhombotin-like 1); LIM domain only protein 2; LIM domain only-2; LIM only 2; LMO2; LMO-2; LMO2 protein; Rbtn2; Rbtn-2; RBTNL1; RHOM2; Rhom-2; rhombotin 2; rhombotin-2; rhombotin-like 1; si:dkey-10o6.5; T-cell translocation gene 2; T-cell translocation protein 2; TTG2; wu:fc83a08; zgc:111930; zlmo2
Gene Symbols Lmo2
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids 1–127 of human LMO2
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4005
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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