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Invitrogen™ LMX1A Polyclonal Antibody
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Catalog No. PIPA5117407
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100 μL
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PIPA5117407 100 μL
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Catalog No. PIPA5117407 Supplier Invitrogen™ Supplier No. PA5117407
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Rabbit Polyclonal Antibody

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The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LMX1A
Applications Western Blot
Classification Polyclonal
Concentration 0.92 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Lmx1a
Gene Accession No. Q9JKU8
Gene Alias dr; dreher; LIM homeobox transcription factor 1 alpha; LIM homeobox transcription factor 1, alpha; LIM homeobox transcription factor 1-alpha; LIM/homeobox protein 1.1; LIM/homeobox protein LMX1A; LMX1; LMX-1; Lmx1.1; LMX-1.1; Lmx1a; MGC87616; shaker short-tail; sst
Gene Symbols Lmx1a
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse LMX1A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110648, 289201
Target Species Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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