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Invitrogen™ LMX1B Polyclonal Antibody
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Catalog No. FEPA5145114
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100 μL
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FEPA5145114 100 μL
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Catalog No. FEPA5145114 Supplier Invitrogen™ Supplier No. PA5145114
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YEKEKDLLSS VSPDESDSVK SEDEDGDMKP AKGQGSQSKG SG Antigen sequence identity: Mouse 100%; Rat 98%.

LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LMX1B
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Lmx1b
Gene Accession No. O60663
Gene Alias LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1
Gene Symbols Lmx1b
Host Species Rabbit
Immunogen Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 169-210. Recombinant protein control fragment (Product #RP-110052).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4010
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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