Invitrogen™ LMX1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534471

Catalog No. PIPA534471

Description

A suggested positive control is A-20 cell lysate. PA5-34471 can be used with blocking peptide PEP-1513.

LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

Specifications

• Antigen: LMX1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lmx1b
• Gene Alias: LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114501, 16917, 4010
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O60663, O88609
• Gene Symbols: Lmx1b
• Immunogen: A 17 amino acid peptide near the carboxy terminus of human LMX1B.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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