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Invitrogen™ LMX1B Polyclonal Antibody
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Catalog No. PIPA592937
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100 μL
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PIPA592937 100 μL
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Catalog No. PIPA592937 Supplier Invitrogen™ Supplier No. PA592937
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YHLGCFCCCV CERQLRKGDE FVLKEGQLLC KGDYEKEKDL LSSVSPDESD SVKSEDEDGD MKPAKGQGSQ SKGSGDDGKD PRRPKRPRTI LTTQQRRAFK ASFEVSSKPC RKVRETLAAE TGLSVRVVQV WFQNQRAKMK KLARRHQQQQ EQQNSQRLGQ EVLSSRMEGM MASYTPLAPP QQQIVAMEQS PYGSSDPFQQ GLTPPQMPGN DSIFHDIDSD TSLTSLSDCF LGSSDVGSLQ ARVGNPIDRL YSMQSSYFAS; Positive Samples: BT-474; Cellular Location: Nucleus.

LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LMX1B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Lmx1b
Gene Accession No. O60663, O88609
Gene Alias LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1
Gene Symbols Lmx1b
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 136-395 of human LMX1B (NP_0023072).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16917, 4010
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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