Invitrogen™ LMX1B Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142403

Catalog No. PIPA5142403

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

LMX1B, LIM homeobox transcription factor 1B, belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning LMX1B-null mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors.

Specifications

• Antigen: LMX1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Lmx1b
• Gene Alias: LIM homeo box transcription factor 1B; LIM homeobox transcription factor 1 beta; LIM homeobox transcription factor 1, beta; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.1; LMX1.2; LMX-1.2; LMX1B; NPS1
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 4010
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60663
• Gene Symbols: Lmx1b
• Immunogen: Peptide with sequence QQALTTSCYFRDRK.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG