Invitrogen™ LNK Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552154

Catalog No. PIPA552154

Description

Immunogen sequence: FDPPKSSRPK LQAACSSIQE VRRCTRLEMP DNLYTFVLKV KDRTDIIFEV GDEQQLNSWM AELSECTGRG LESTEAEMHI PSALEPSTSS SPRGSTDSLN QGASPGGLLD PACQKTDHFL SCYPWFH Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 77%.

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.

Specifications

• Antigen: LNK
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SH2B3
• Gene Alias: AI429800; IDDM20; linker of T-cell receptor pathways; LNK; Lymphocyte adapter protein; lymphocyte-specific adapter protein Lnk; SH2B adapter protein 3; SH2B adaptor protein 3; Sh2b3; Signal transduction protein Lnk
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10019
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UQQ2
• Gene Symbols: SH2B3
• Immunogen: Recombinant protein corresponding to Human LNK. Recombinant protein control fragment (Product #RP-102117).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG