Alfa Aesar™ Lovastatin, 97%

Manufacturer: Alfa Aesar™ H52792-14

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Catalog No. AAH5279214

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    Chemical Identifiers

    CAS 75330-75-5
    Molecular Formula C24H36O5
    Formula Weight 404.56g/mol
    MDL Number MFCD00072164
    Synonym Mevacor
    Chemical Name or Material Lovastatin

    Specifications

    Melting Point 175°C
    Quantity 25g
    CAS 75330-75-5
    Molecular Formula C24H36O5
    Formula Weight 404.56g/mol
    MDL Number MFCD00072164
    Synonym Mevacor
    Health Hazard 1 Warning
    Health Hazard 2 GHS H Statement
    H302-H315-H319-H335
    Harmful if swallowed.
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.
    Health Hazard 3 GHS P Statement
    P261-P280-P305+P351+P338-P304+P340-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    RTECS Number EK7907000
    Chemical Name or Material Lovastatin
    Assay 97%

    Description

    Applications
    Lovastatin is a cholesterol lowering drug and competitive inhibitor of HMG-CoA reductase, a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. It increases cellular resistance to anticancer agents such as doxorubicin and induces apoptosis in myeloma cells. It causes cell cycle arrest in G1 and G2/M phases.

    Solubility
    Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), methanol, chloroform, acetone, acetonitrile, DMF, and water (0.4 µg/ml).

    Notes
    Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

    GHS H Statement
    H302-H315-H319-H335
    Harmful if swallowed.
    Causes skin irritation.
    Causes serious eye irritation.
    May cause respiratory irritation.

    GHS P Statement
    P261-P280-P305+P351+P338-P304+P340-P405-P501a
    Avoid breathing dust/fume/gas/mist/vapors/spray.
    Wear protective gloves/protective clothing/eye protection/face protection.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Warning

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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