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Tocris Bioscience™ Lovastatin
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Catalog No. 153050
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50 mg
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Catalog No. Quantity
15-305-0 50 mg
15-301-0 10 mg
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Catalog No. 15-305-0 Supplier Tocris Bioscience™ Supplier No. 1530/50
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Description

Potent HMG-CoA reductase inhibitor

Potent, competitive inhibitor of HMG-CoA reductase (Ki = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo. Indirectly inhibits Rho-GTPase activity by depleting intracellular pool of isoprene residues. Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro. Inactive lactam prodrug of lovastatin hydroxy acid, naturally bioactivated in vivo following oral administration.

Chemical Identifiers

CAS 75330-75-5
Molecular Formula C24H36O5

Specifications

Quantity 50 mg
Formula Weight 404.54
Purity >98%
Molecular Weight (g/mol) 404.55
Chemical Name or Material Lovastatin

Safety and Handling

Recommended Storage Store at Room Temperature
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