Invitrogen™ LOX Monoclonal Antibody (OTI9G6)

Catalog No.	Quantity
PIMA525033	100 μL

Catalog No. PIMA525033 Supplier Invitrogen™ Supplier No. MA525033

Description

Mouse Monoclonal Antibody

LOX Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.

Specifications

• Antigen: LOX
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: OTI9G6
• Concentration: 1.00 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: LOX
• Gene Accession No.: P28300
• Gene Alias: AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160
• Gene Symbols: LOX
• Host Species: Mouse
• Immunogen: Human recombinant protein fragment corresponding to amino acids 22-168 of LOX produced in HEK293T cell.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4015
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1