Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ LOX Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA116955

Catalog No. 01-950-184


Only null left
Add to Cart

Description

Description

This antibody is 92% homologous to chicken, zebrafish, and xenopus.

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LOX
Polyclonal
Unconjugated
LOX
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160
Rabbit
Affinity chromatography
RUO
100525278, 16948, 24914, 280841, 4015
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.02% sodium azide
P16636, P28300, P28301, P33072, P45845
LOX
Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein.
50 μL
Primary
Human, Mouse, Rat, Bovine, Pig
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.