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Invitrogen™ LOX Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA116955
Description
This antibody is 92% homologous to chicken, zebrafish, and xenopus.
Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
Specifications
LOX | |
Polyclonal | |
Unconjugated | |
LOX | |
AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160 | |
Rabbit | |
Affinity chromatography | |
RUO | |
100525278, 16948, 24914, 280841, 4015 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
P16636, P28300, P28301, P33072, P45845 | |
LOX | |
Cocktail of two synthetic peptides between amino acids 300-350 and amino acids 200-300 of the human LOX protein. | |
50 μL | |
Primary | |
Human, Mouse, Rat, Bovine, Pig | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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