Invitrogen™ LOXL1 Monoclonal Antibody (C1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543676

Catalog No. PIMA543676

Description

LOXL1 Monoclonal Antibody for Western Blot, IHC (P)

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q08397
• Gene Symbols: Loxl1
• Immunogen: Recombinant protein Lysyl Oxidase Like Protein 1. The antigen corresponds to amino acid range 369-574 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: C1
• Conjugate: Unconjugated
• Gene: Loxl1
• Gene Alias: cross-linking enzyme; LOL; Lox2; LOXL; LOXL1; Lysyl oxidase 2; lysyl oxidase homolog 1; lysyl oxidase like 1; lysyl oxidase-like 1; lysyl oxidase-like protein 1
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 4016
• Content And Storage: -20°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov