LOXL2 Mouse anti-Human, Clone: OTI2A7, lyophilized, TrueMAB™

Catalog No.	Quantity
50-166-8273	100 μg

Catalog No. 50-166-8273 Supplier OriGene Supplier No. CF807441

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.

Specifications

• Antigen: LOXL2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2A7
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: LOXL2
• Gene Accession No.: Q9Y4K0
• Gene Alias: LOR, LOR2, WS9-14
• Gene Symbols: LOXL2
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 152-450 of human LOXL2 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4017
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1