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LOXL2 Mouse anti-Human, Clone: OTI2A7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF807441

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.Specifications
LOXL2 | |
Monoclonal | |
Unconjugated | |
LOXL2 | |
LOR, LOR2, WS9-14 | |
Mouse | |
Affinity Chromatography | |
RUO | |
4017 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI2A7 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9Y4K0 | |
LOXL2 | |
Human recombit protein fragment corresponding to amino acids 152-450 of human LOXL2 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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