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LOXL2 Mouse anti-Human, Clone: OTI2A7, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF807441

Encompass_Preferred

Catalog No. 50-166-8273


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Lysyl Oxidase (LO) is an extracellular, copper-dependent enzyme that initiates the cross-linking of collagens and elastin by catalyzing the oxidative deamination of peptidyl lysine to alpha-aminoadipic-delta-semialdehyde. Members of LO family have diverse functions which include tumor suppression and cell adhesion and senescence. LOXL2, a 87KDa protein, is a novel member of this family. It contains 3 potential N-linked glycosylation sites, 4 scavenger receptor cysteine-rich (SRCR) domains and highly conserved copper-binding and Lysyl-tyrosylquinone cofactor sites. It is a component of extracellular matrix that might be involved in cell adhesion and senescence. Role of LOXL2 has been implicated in maligt transformation.
Specifications

Specifications

LOXL2
Monoclonal
Unconjugated
LOXL2
LOR, LOR2, WS9-14
Mouse
Affinity Chromatography
RUO
4017
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI2A7
PBS with 8% trehalose and no preservative; pH 7.3
Q9Y4K0
LOXL2
Human recombit protein fragment corresponding to amino acids 152-450 of human LOXL2 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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