Invitrogen™ LOXL3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5145270

Catalog No. FEPA5145270

Description

LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LOXL3
• Gene Alias: Lor2; LOW QUALITY PROTEIN: lysyl oxidase homolog 3; LOXL; Loxl2; Loxl3; Lysyl oxidase homolog 3; lysyl oxidase like 3; lysyl oxidase-like 2; lysyl oxidase-like 3; lysyl oxidase-like protein 3; Lysyl oxidase-related protein 2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100512652, 16950, 312478, 84695
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
• Gene Accession No.: P58215, Q9Z175
• Gene Symbols: LOXL3
• Immunogen: Recombinant Human LOXL3 protein, Thr519-Asn726 (Accession #P58215).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Pig
• Product Type: Antibody
• Isotype: IgG