Invitrogen™ LOXL3a Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143378

Catalog No. PIPA5143378

Description

Store as concentrated solution. Centrifuge briefly prior to opening vial.

LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL3a
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Lor2; LOW QUALITY PROTEIN: lysyl oxidase homolog 3; LOXL; Loxl2; Loxl3; Lysyl oxidase homolog 3; lysyl oxidase like 3; lysyl oxidase-like 2; lysyl oxidase-like 3; lysyl oxidase-like protein 3; Lysyl oxidase-related protein 2
• Immunogen: The immunogen used to generate this antibody corresponds to zebrafish Loxl3a.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed)
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Target Species: Zebrafish
• Product Type: Antibody
• Isotype: IgG