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Tocris Bioscience™ LP 922056
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Catalog No. 669110
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10 mg
50 mg
Catalog No. Quantity
66-911-0 10 mg
66-915-0 50 mg
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Catalog No. 66-911-0

Supplier: Tocris Bioscience™ 6691/10

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Description

Notum inhibitor; activates Wnt signaling

LP 922056 is a notum pectinacetylesterase inhibitor. LP 922056 activates wnt signaling in vitro (EC50 values are 21 nM in human and 55 nM in mouse cell-based assay). It increases cortical bone thickness in mouse model of bone growth. LP 922056 also inhibits growth of Apc-mutant cell lines and proliferation of intestinal adenomas in vivo.

Specifications

Chemical Name or Material 2-[(6-Chloro-7-cyclopropylthieno[3,2-d]pyrimidin-4-yl)thio]acetic acid
CAS 1365060-22-5
Quantity 10 mg
Molecular Formula C11H9ClN2O2S2
Purity 98%
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